Neuromuscular and Cognitive Fatigue During a 24 Hour Treadmill Running Exercise

Neuromuscular and Cognitive Fatigue During a 24h Treadmill Running Exercise.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00428779

Enrollment

Registered

2007-01-30

Start date

2007-09-30

Completion date

2007-12-31

Last updated

2009-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Running during 24 hours, Voluntary evoked force on the muscles, Electrically evoked force on the muscles, EMG activity, Muscle biopsy, subjects will be recruited among experienced ultra-runners

Brief summary

The main purpose of the present study is to determine the relative contributions of central and peripheral fatigue during an ultra-endurance exercise.

Detailed description

For that purpose, 14 subjects running 24 hours on a treadmill will be compared with a control group being awake during the same period. Subjects who running will have electrically evoked forces on the muscles associated EMG activity, blood samples and muscle biopsy.

Interventions

PROCEDURErunning during 24 hours without sleep

patients running during 24 hours without sleep

OTHERno sleeping

patients without sleep during 24 hours

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* The subjects of the experimental group will be recruited among experienced ultra-runners . They all have run at least a 12 hour race or longer. * The control group will be recruited among experienced ultra-runners . Age of control group will be age experimental group more or less 2 years.

Exclusion criteria

* The subjects will not be selected if: * they were injured in the 3 months before the experiment * they had a tendon or joint pathology that could impair strength measurements. * they participate to an other experiment at the same time

Design outcomes

Primary

Measure	Time frame
-Voluntary and electrically evoked forces on the contracted muscles	24 hours

Secondary

Measure	Time frame
Electrically evoked forces on the relaxed muscles and associated EMG activity	24 hours
Blood samples before the exercise	every 4 hours
Muscle biopsy (vastus lateralis)	before and after the exercise

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026