Long-Term IOP Fluctuation and VF Progression After Triple Procedure

Long-Term Intraocular Pressure Fluctuation and Visual Field Progression in Glaucoma Patients With Low Intraocular Pressure After Triple Procedure

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00428740

Enrollment

300

Registered

2007-01-30

Start date

2005-10-31

Completion date

2005-12-31

Last updated

2007-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Filtering Surgery, Glaucoma, Intraocular Pressure

Brief summary

Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for patients with coexisting glaucoma and visually significant cataracts.

Detailed description

Previous studies reported that lowering intraocular pressure (IOP) slowed the advancement of visual field damage in glaucoma patients. However, even if the IOP can been substantially lowered, reduction of mean and peak IOP does not always prevent visual field progression.We believe that the long-term IOP fluctuation may play a significant role in visual field deterioration in those patients.

Interventions

None listed

Study design

Observational model

DEFINED_POPULATION

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. Underwent triple procedure 2. At leas 3 years of follow-up after surgery 3. IOP \<18mmHg at each postoperative visit 4. A minimum of 5 visual field examinations 5. A reference visual field defect score of 16 or less 6. Good reliability indices of visual field

Exclusion criteria

1. Any other significant ocular diseases or intraocular surgical histories, 2. Diseases that may affect visual field or diabetes

Countries

South Korea

Outcome results