Full-Leg vs Below-Knee Elastic Stockings for Prevention of the Post-Thrombotic Syndrome

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00426075

Enrollment

Unknown

Registered

2007-01-24

Start date

2006-01-31

Completion date

Unknown

Last updated

2008-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep Vein Thrombosis

Keywords

Deep vein thrombosis of the lower extremities

Brief summary

Prospective controlled randomized clinical trial. Consecutive patients with acute proximal deep vein thrombosis of the lower extremities, with or without contemporary manifestations of pulmonary embolism, are randomized to receive either a below-knee or a full-leg graduated compression (30-40 mm Hg at the ankle) elastic stocking for prevention of the post-thrombotic syndrome (PTS). All patients are followed up to three years to assess the development of the PTS, defined according to a validated clinical score (the Villalta scale). The rate of PTS is compared between the two study groups. In addition, there is an assessment of patients' compliance and tolerability of the two different devices.

Interventions

DEVICEElastic stockings

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* First episode of proximal deep vein thrombosis, as shown by compression ultrasound

Exclusion criteria

* Previous ipsilateral deep vein thrombosis * Preexisting chronic venous insufficiency * Bilateral deep vein thrombosis * Life expectancy lower than 1 year * Severe arteriopathy of the lower limbs * Known allergy to elastic stockings * Lack of written informed consensus

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026