Chronic Phantom Limb Pain
Conditions
Brief summary
This is a study to assess the possible benefit of duloxetine in the treatment of chronic phantom limb pain.
Interventions
DRUGDuloxetine
Sponsors
Baylor College of Medicine
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Chronic PLP \> 6 months 2. Short-Form McGill Pain Questionnaire Sensory Pain Rating Index raw score ≥ 16 3. Age ≥ 18 years old 4. Inpatient or Outpatient 5. Able to come to all appointments, in the opinion of the investigator 6. Able to give informed consent, in opinion of investigator
Exclusion criteria
1. Current Major Depressive disorder, Anxiety Disorder, or Psychotic disorder assessed by the Mini International Neuropsychiatric Interview (MINI) 2. Substance abuse or dependence within the last six months, as assessed by the MINI 3. Known Diabetes Mellitus to exclude diabetic peripheral neuropathy 4. History of coronary artery disease, hepatic disease, renal disease 5. Other pain syndromes 6. Any unstable medical conditions in the opinion of the investigator 7. Other psychotropic medications excluding hypnotics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| McGill Short Form Pain Questionairre | — |
Secondary
| Measure | Time frame |
|---|---|
| Fiser Side effect scale | — |
| visual analog pain scale | — |
| Present Pain intensity | — |
| Tylenol # 3 consumption | — |
Countries
United States
Outcome results
None listed