Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00419627

Enrollment

160

Registered

2007-01-08

Start date

2007-02-28

Completion date

Unknown

Last updated

2007-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Neoplasms, Colorectal Neoplasms, Ovarian Cancer, Pancreatic Neoplasms, Stomach Neoplasms

Keywords

proteomics of solid tumors

Brief summary

The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

Detailed description

The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.

Interventions

None listed

Study design

Observational model

NATURAL_HISTORY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Inclusion criteria

* Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas

Exclusion criteria

* Withdrawal of consent * Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation

Countries

Israel

Contacts

Primary ContactItamar Ashkenazi, M.D.

i_ashkenazi@yahoo.com972-4-6304761

Outcome results