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Early Movements as a Predictor of Future Developmental Delay

Analysis of Movements of Singletons and Infants of Multiple Fetus Pregnancy as a Predictor of Developmental Delay

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00418808
Enrollment
50
Registered
2007-01-05
Start date
2006-08-31
Completion date
2009-08-31
Last updated
2007-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Palsy, Premature Birth

Keywords

motor, development, multiple pregnancies, general movement, video recording

Brief summary

Cerebral Palsy (CP) is a major developmental problem. Major risk groups of CP, are preterm infants and multiple pregnancies. Previous studies using the General Movements methodology demonstrated early identification of CP, as early as 3 month of age. This method was implemented mainly on preterm infants this study goal is to enlarge the scope of the methodology to infants of multiple pregnancies. A second goal is to study early motor development and its future consequences by comparing the development of the infants of the same multiple pregnancy.

Detailed description

Cerebral Palsy (CP) is a motor development problem with a prevalence of 2 per 1000 live birth. There are many etiologies to the syndrome such as: brain malformations, infections during pregnancy, pre and perinatal, anoxic brain damage etc. A high risk group for these causes is preterm infants and infants of multiple pregnancies. Major motor deficits or brain insults are recognizable at early weeks but most of them are more subtle and are recognized at the age of one to two years. The General Movements methodology was developed by Prechtl HF is aimed to identify motor development deficits as early as 3 month. The methodology is using video recording to describe a trajectory of the development of spontaneous movements between birth and 3 month. Deviation from the trajectory was highly correlated with future motor mal-development. In our work we will study the motor development of infants of multiple pregnancies. These infants are one of the risk groups to develop CP. We will use the General movements methodology to identify CP as early as possible. It will generalize its predicative power to this risk group. Moreover, we will enlarge our knowledge of motor development by comparing the development of infants of the same pregnancy.

Interventions

None listed

Sponsors

Sheba Medical Center
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
2 Days to 4 Months
Healthy volunteers
No

Inclusion criteria

for preterm infants: * preterm infant under 37 weeks * Normal or intraventricular hemorrhage grade I at U/S examination * No neurological family history * No maternal drug use with neurological effect during pregnancy * Normal prenatal history such as: no evidence of hypoxic ischemic encephalopathy * No convulsions * Normal karyotype * No major congenital heart defect * Dizygotic twins Inclusion Criteria for full term infants: * Normal physiological examination * No neurological family history * No maternal drug use with neurological effect during pregnancy

Countries

Israel

Contacts

Primary ContactOmer Bar-Yosef, Dr.
omerbary@gmail.com972-3-5302896

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026