Healthy
Conditions
Keywords
Normal Controls
Brief summary
Trans Cranial Magnetic Stimulation (TMS) over dorsal visual system will disturb the ability to identify objects with decreased level of fragmentation
Detailed description
The participants performed two tasks under three different TMS conditions: no TMS, 10Hz TMS for over the dorsal stream (PO3 EEG site) or over the vertex. First they performed a perceptual closure task which asked them to identify an object in a series of six progressively less degraded pictures. Then, they also performed a control task previously shown not to be mediated by the LOC and not to be impaired in schizophrenia: The perception of illusory contours.
Interventions
DEVICENo TMS intervention
In the no TMS condition, no simulation was given and no coil placed near participants' heads.
DEVICETMS over the PO3 EEG site
10Hz TMS over the dorsal stream (PO3 EEG site)
DEVICETMS over the vertex
10Hz TMS for over vertex.
Sponsors
Sheba Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Normal controls
Exclusion criteria
* neurological, ophthalmological or psychiatric problems * family history of schizophrenia * left handed
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Results of the study assignments performed by the participants during the study. | The participants performed the tasks once during their study visit | The subjects performed 2 tasks: The primary dependent measures consisted of the level of detail needed for correct object identification, response accuracy, and response time in milliseconds for correct responses. Illusory Contour Task: Subjects also performed a pulsed pedestal task, Participants were shown 55 drawings for 500 ms each. Some drawings contained partial contours which defined a geometric shape, while in others the contours did not define a shape. Participants were asked to indicate whether they recognized a geometric shape or not. Accuracy and response time were measured. |
Countries
Israel
Outcome results
None listed