Additional Glucose Lowering and Anti-Inflammatory Effects by Acarbose and Alcohol in Subjects With Impaired Glucose Tolerance or Mild Type 2 Diabetes

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00417950

Enrollment

Registered

2007-01-04

Start date

2007-01-31

Completion date

Unknown

Last updated

2007-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus, Impaired Glucose Tolerance

Keywords

diabetes, acarbose, alcohol, inflammation, oxidative stress, Mild diabetes mellitus

Brief summary

To understand if acarbose, an alpha-glucosidase inhibitor usually for treating diabetes, will further lower post meal glucose and inflammatory state when taking together with moderate amount of alcohol during meal tolerance test in subjects with impaired glucose tolerance or mild diabetes.

Interventions

DRUGAcarbose

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

25 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Subjects with mild diabetes without prior medications or impaired glucose tolerance

Exclusion criteria

* Pregnancy * Recent major cardiac, renal and hepatic disease * Intolerance to alcohol * Allergy to acarbose treatment

Design outcomes

Primary

Measure	Time frame
Postprandial hyperglycemia	—

Secondary

Measure	Time frame
Postprandial inflammatory responses	—
Postprandial oxidative stress	—

Countries

Taiwan

Contacts

Primary ContactI Te Lee, MD, MS

itlee@vghtc.gov.tw886-4-23592525

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026