Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment of Sever Acne

Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00416585

Enrollment

Registered

2006-12-28

Start date

2005-10-31

Completion date

2006-11-30

Last updated

2008-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne

Keywords

acne, isotretinoin, calcium. vitamin D

Brief summary

serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne

Detailed description

few studies has been done of serum levels Ca, P, PTH and vitamin D metabolites in patients receiving isotretinoin .In this study we measured serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne in 30 patients . the patients had no kown skeletal, endocrine ,renal and gastrointestinal disorders.

Interventions

DRUGisotretinoin (Roaccutane)

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* sever acne

Exclusion criteria

* renal disorders * gastrointestinal disorders * skeletal disorders * endocrine disorders * drugs such as glucocorticoids , thiazide diuretics, mineral multivitamins, anti acids, tetracyclines

Design outcomes

Primary

Measure	Time frame
serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray before the treatment	—

Secondary

Measure	Time frame
serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray after the treatment	—

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026