Effect of Weight Reduction on Inflammatory Markers and Genes Expression in Obese Individuals

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00416156

Enrollment

Registered

2006-12-27

Start date

2005-05-31

Completion date

2005-11-30

Last updated

2006-12-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammation, Obesity

Keywords

Obesity, Inflammation

Brief summary

To investigate whether weight reduction by life style modification for 12 weeks will improve circulating inflammatory markers, adipocytokines as well as gene expression of proinflammatory protein obtained from circulating monocytes from obese individuals.

Interventions

BEHAVIORALLifestyle modification

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Nondiabetes obese individuals with BMI greater than 27 kgs/m2

Exclusion criteria

* Diabetes * Abnormal hepatic, renal and cardiac function

Design outcomes

Primary

Measure	Time frame
Inflammatory responses after weight reduction	—

Secondary

Measure	Time frame
BMI	—
Circulating inflammatory markers	—
Adipocytokines	—
Gene Expression from mononuclear cells	—

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026