Mechanism and Prevention of Remote Organ Injury Following Ruptured Aortic Aneurysm

Phase 1 Study of Complement Activation Following Ruptured Abdominal Aortic Aneurysm: Combining Human Observation With Animal Experimentation to Establish a Framework for Human Therapy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00416000

Enrollment

Registered

2006-12-27

Start date

2006-01-31

Completion date

2010-12-31

Last updated

2014-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Aortic Aneurysm

Keywords

Open/Elective EVAR patients

Brief summary

It has been estimated that 80% of deaths from abdominal aortic aneurysms results from rupture. Endovascular Aneurysm Repair (EVAR) has been applied to RAAA (Ruptured Abdominal Aortic Aneurysm) patients with reports of improvements. Despite the use of EVAR, patients have developed complications with lung and kidney function. This study will investigate certain biochemical processes that will potentially reduce these complications. Knowledge gained from this study may also be used to further research in this field through larger studies.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

30 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Open/Elective EVAR patients

Exclusion criteria

* Patients who do not present with abdominal aortic aneurysms or ruptured abdominal aortic aneurysm

Design outcomes

Primary

Measure	Time frame
Mortality	30 days

Secondary

Measure	Time frame
multiple organ failure	30 days

Countries

Canada

Outcome results