Myocardial Contrast Echocardiography in Congenital Heart Disease

Quantification of the Myocardial Microcirculation by Contrast Echocardiography In Adult Patients With Congenital Heart Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00412685

Enrollment

Registered

2006-12-18

Start date

2006-08-31

Completion date

2008-12-31

Last updated

2015-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D-Transposition of Great Arteries, Tetralogy of Fallot

Brief summary

Patients with congenital heart disease in whom the right ventricle is exposed to pressure or volume overload show progressive systolic dysfunction of the right ventricle, the fact of which conveys substantial morbidity and mortality. The aim of this study is to investigate the myocardial perfusion in these patients by myocardial contrast echocardiography (MCE) in order to determine whether disturbed blood flow plays a role in the development of right ventricular systolic dysfunction.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* D-TGA or Fallot-Tetralogy or Healthy person * written informed consent * Age \>= 18 years

Exclusion criteria

* Anaemia * Pregnancy and breast feeding * Diabetes mellitus * Contraindications to stress testing (ergometry or adenosine) * Known adverse reaction or hypersensitivity against V08DA (SonoVue) or its components or against adenosine

Countries

Switzerland

Outcome results