Investigation of Genetic Risk of Atrial Fibrillation

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00412438

Enrollment

1000

Registered

2006-12-18

Start date

2006-10-31

Completion date

Unknown

Last updated

2006-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Keywords

Atrial Fibrillation

Brief summary

The atrial fibrillation (AF) is the most common cardiac rhythm disturbance that is responsible for substantial morbidity and mortality independent of associated heart disease or other risk factors. Even in the absence of preexisting cardiovascular disease, AF remains significantly associated with excess mortality rates. The current unsatisfactory treatment for AF comes from lack of understanding of the pathophysiology of AF. The purpose of this study is to identify gene polymorphisms that confer susceptibility to atrial fibrillation. Patients with AF（N=500） and healthy volunteer（N=1000） without AF are enrolled in this study. Patients with coronary artery disease, severe valvular heart disease, cardiomyopathy or heart failure were excluded from the study.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Clinical diagnosis of atrial fibirillation

Exclusion criteria

* coronary artery disease * severe valvular heart disease * cardiomyopathy * heart failure

Countries

Japan

Contacts

Primary ContactKenji Yasui, MD, PhD

kenji@riem.nagoya-u.ac.jp+81-52-788-6211

Backup ContactMasaki Yamauchi, MD

g030744d@mbox.nagoya-u.ac.jp+81-52-788-6210

Outcome results