Insulin Resistance and Hypertensive Disorders in Pregnancy

The Role of Insulin Resistance in Gestational Hypertension and in Preeclampsia.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00412230

Enrollment

100

Registered

2006-12-18

Start date

2006-10-31

Completion date

2008-06-30

Last updated

2009-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus in Pregnancy, Hypertension in Pregnancy

Keywords

Pre-eclampsia, Gestational diabetes, Insulin resistance, hypertension in pregnancy

Brief summary

The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester. Furthermore, markers of vascular and placental injuries, of oxidative stress and inflammation will be evaluated.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* PCOS, BMI\>/=30 * previous pregnancy affected by hypertension or gestational diabetes * thrombophilia * Type I or II diabetes mellitus * autoimmune diseases * twin pregnancy * renal diseases * previous pre-eclampsia in relatives

Countries

Italy

Outcome results