Novel Therapy of PAD by Combined Transplantation of BMCs

Transplantation of Autologous Mononuclear Bone Marrow Stem Cells in Patients With Peripheral Arterial Disease (TAM-PAD Study)

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00411840

Enrollment

100

Registered

2006-12-15

Start date

2004-07-31

Completion date

Unknown

Last updated

2006-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral Arterial Disease

Keywords

stem cell therapy, peripheral arterial disease, limb ischemia

Brief summary

We analyze the effects of combined intramuscular and intraarterial transplantation of BMCs in patients with PAD. BMCs were transplanted into the ischemic limb. After 2 and 13 months walking distance and perfusion indices were monitored.

Interventions

PROCEDUREintraarterial and intramuscular injection of BMCs

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* severe limb ischemia

Exclusion criteria

* infectious disease * cancer

Design outcomes

Primary

Measure	Time frame
ABI, walking distance, capillary-venous oxygen saturation, venous occlusion plethysmography	—

Secondary

Measure	Time frame
feasibility	—

Countries

Germany

Contacts

Primary ContactThomas Bartsch, MD

bartsch@med.uni-duesseldorf.de+492118118800

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026