Healthy
Conditions
Keywords
Physically fit volunteers
Brief summary
The purpose of this study is to determine the effect of daily use of Naproxen (a commonly used over-the-counter NSAID) on the physical performance of athletes, as measured by maximum oxygen consumption.
Interventions
DRUGNaproxen
Sponsors
University of Oklahoma
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
1. Age equal to or greater than18 years of age 2. No history of allergy or adverse reaction to any NSAID 3. No use of any NSAID in past 2 weeks 4. No history of peptic ulcer disease (PUD), gastroesophageal disease (GERD), or gastritis 5. No major medical history including but not limited to diabetes, hypertension, asthma, kidney disease and coronary artery disease 6. Currently not taking any medication including oral contraceptives
Exclusion criteria
1. Age \< 18 years of age 2. History of allergy or adverse reaction to any NSAID 3. Use of any NSAID in past 2 weeks 4. History of a bleeding disorder 5. History of PUD, GERD, or gastritis 6. Pregnant 7. A medical history of diabetes, hypertension, asthma, kidney disease or coronary artery disease 8. Taking any medication including oral contraceptives
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effects on physical performance in terms of maximum oxygen consumption | — |
Countries
United States
Outcome results
None listed