Vasospastic Syndrome
Conditions
Keywords
vasospastic women, controls, core cooling, core warming, external cooling, external warming, LDF, choroidal blood flow, temperature, vasospastic subjects, normal subjects
Brief summary
This study tests whether women with Vasospastic Syndrome (VS) react more intensive than controls with distal vasomotions and choroidal blood flow changes to internal cooling/warming and external cooling/warming.
Detailed description
Distal vasomotions and choroidal blood flow changes to internal cooling/warming and external cooling/warming was studied in VS and controls.Core cooling was induced by drinking of 250g ice/water mixture (4°C). Core warming was induced by drinking of 250g warm water (55°C). The study was controlled with respect to posture and room temperature.
Interventions
None listed
Sponsors
University Hospital, Basel, Switzerland
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
19 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* women * luteal phase or contraceptives * 19-35 years
Exclusion criteria
* somatic diseases * psychiatric diseases * BMI \> 25 * BMI \< 18
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LDF velocity | repeated after each challenge |
| core body temperature | repeated after each challenge |
| corneal temperature | repeated after each challenge |
| LDF blood flow | repeated after each challenge |
| finger skin temperature | repeated after each challenge |
Secondary
| Measure | Time frame |
|---|---|
| subjective ratings of thermal comfort | repeated after each challenge |
| subjective sleepiness | repeated after each challenge |
Countries
Switzerland
Outcome results
None listed