Investigation of Genetic Risk of Metabolic Syndrome in Company Employee (NGK Study)

Assessment of Genetic Risk of Metabolic Syndrome in Company Employee and Making New Health Guidance Program (NGK Study)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00408824

Enrollment

4000

Registered

2006-12-07

Start date

2006-09-30

Completion date

Unknown

Last updated

2007-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus, Healthy, Hyperlipidemia, Hypertension, Metabolic Syndrome X

Keywords

insulin resistance, adipocytokine, Metabolic syndrome, Diabetes

Brief summary

The metabolic syndrome is a highly prevalent disorder, which causes atherosclerotic cardiovascular disease and is closely associated with insulin resistance. The alteration of the secretion of adipocytokines from accumulated visceral adipose tissue in the obese induces insulin resistance. The purpose of this study is to identify gene polymorphisms that confer susceptibility to the metabolic syndrome and to make up a new health guidance program based on genetic risk assessment. About 25% of male employees over 45 years old in a certain company are diagnosed with the metabolic syndrome in medical examination. We, the researchers at Nagoya University, will analyze gene polymorphism and various biomarkers of over 3500 company employees.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

20 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy subjects who work for a certain company

Countries

Japan

Contacts

Primary ContactKenji Yasui, MD, PhD

kenji@riem.nagoya-u.ac.jp+81-52-788-6211

Outcome results