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Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study

Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00408265
Enrollment
80
Registered
2006-12-06
Start date
2004-01-31
Completion date
2007-03-31
Last updated
2011-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nicotine Dependence

Keywords

Nicotine Dependence, Contingency Management

Brief summary

The purpose of this study is to compare the effects of self-help materials for smoking cessation and self-help materials for smoking cessation plus prize-based contingency management (CM), in which prize incentives are available for breath and saliva samples that indicate smoking abstinence, in substance abuse treatment patients who want to quit smoking.

Detailed description

The specific aims of this study are: (1) to examine the efficacy of self-help materials compared to self-help materials plus prize contingency management (CM) for smoking abstinence in substance abuse treatment patients and (2) examine the effects of smoking abstinence on substance use and substance treatment retention. To address these specific aims, cigarette smokers entering treatment for alcohol, cocaine or heroin abuse or dependence, who report daily smoking (at least one cigarette per day) for the past year, and who meet other inclusion and exclusion criteria, are randomly assigned to receive self-help materials or self-help materials plus CM. Individuals in the CM group have the opportunity to win prizes, worth on average $1, $20, or $100, when they meet smoking abstinence criteria (CO \< 8ppm and salivary cotinine \< 10ng/mL). Participants meet with research staff 4 times/week during Weeks 1-4, 2 times/week during Weeks 5-8 and 1 time/week during Weeks 9-12. Follow-up interviews are scheduled 1, 3 and 6 months following the smoking quit date.

Interventions

BEHAVIORALContingency Management

Sponsors

National Institute on Alcohol Abuse and Alcoholism (NIAAA)
CollaboratorNIH
UConn Health
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* meets diagnostic criteria for alcohol, cocaine or heroin abuse or dependence * self-report daily smoking for at least the past year * CO \> 8ppm * interested in quitting smoking while in treatment, * minimum age 18 years old * willing to provide names, addresses and phone numbers of individuals to assist in locating the patient for follow-up evaluations * English speaking

Exclusion criteria

* current use of NRT * current use of bupropion * serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, suicide risk) * dementia (Mini-mental status score of \<23) * currently participating in another CM study at the clinic * in recovery for pathological gambling

Design outcomes

Primary

MeasureTime frame
Percent negative CO readings
Percent negative cotinine readings
Longest period of continuous abstinence

Secondary

MeasureTime frame
Self-reported frequency and severity of smoking
Treatment retention
Objective substance use
Self-reported substance use

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026