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Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00404469
Enrollment
39
Registered
2006-11-28
Start date
2006-03-31
Completion date
2007-11-30
Last updated
2008-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellar Tendinopathy / Jumpers Knee

Brief summary

We will investigate the effect of peritendinous corticosteroid injections, eccentric training and heavy resistance training in male patellar tendinopathy patients. The purpose is to compare the clinical effect of these three treatments in a randomised controlled trial. Also we wish to investigate the treatment mechanisms responsible for the effectiveness of the three treatments.

Detailed description

3 interventions groups as described above (n=13 in each group) 12 weeks intervention period. Clinical assessments before and after intervention: VAS, VISA, Tendon thickness, Doppler us activity. Before and after intervention tendon biopsies will be taken and analyzed for crosslinks and fibril diameter. Also tendon mechanical properties will be measured. Tendon and muscle structural properties will be measured with MRI. Treatment satisfaction will be stated after intervention period.

Interventions

PROCEDUREperitendinous corticosteroid injections

1 ml of40mg/ml methylprednisolone acetate at 0 and 4 weeks. 2 week observational

PROCEDUREeccentric decline squat training

eccentric decline unilateral squats performed twice daily. for 12 weeks

Heavy slow resistance training for knee extensors. 3/week. total of 12 weeks

Sponsors

Bispebjerg Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
MALE
Age
18 Years to 55 Years
Healthy volunteers
No

Inclusion criteria

* Clinical patellar tendinopathy pain. * Tendon swelling * Hypoechoic * Doppler activity in tendon

Exclusion criteria

* Previous knee surgery * diabetes * arthritis * previous steroid injections

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026