Treatment of Acute Asthma in ER With Combination of Systemic Steroids and Inhaled Steroids

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00397267

Enrollment

120

Registered

2006-11-09

Start date

2007-01-31

Completion date

2007-12-31

Last updated

2006-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma Exacerbation

Keywords

Dyspnea, Cough

Brief summary

We assume that the combination of systemic steroids and inhaled steroid in the first hour of treatment in the ER will decrease the admission rate and improve faster the pulmonary function. 120 patients refferd to the ER due to asthma attack aged 18-60 with PFR \< 60% 0o predicted will participate in the study after giving informed consent. The usual treatment in the ER is inhalation of Beta 2 short acting and I.V solumedrol 120 mg . The study group will recieve in addition 3 inhalation of Budesonide 1000 microgram each during the first hour. The controlled group will recieve Nacl 0.9% PFR will be followed 0 30 60 120 min.

Detailed description

Primary end points- PFT improvment and admission rate.

Interventions

DRUGinhalation of corticosteroids

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Asthmatic patients aged 18-60 with PFR \< 60% of predicted

Exclusion criteria

* Patients with other chronic diseases * cardiac renal hepatic etc will be excluded

Design outcomes

Primary

Measure	Time frame
PFT improvment	—
Admission rate	—

Countries

Israel

Contacts

Primary ContactDov Heimer M.D. Heimer, AS. Proffessor

heimerd@clalit.org.il972 8 6400807

Backup ContactLUNA Avnon, M.D

972 8 6403024

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026