The Role of the Vagus Nerve in Tumor-to-Brain Communication in Lung Cancer Patients

Does the Vagus Nerve Play a Role in Tumor-to-Brain Communication? a Preliminary Study in Patients With Newly Diagnosed Lung Cancer

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00397124

Enrollment

Registered

2006-11-08

Start date

2002-04-30

Completion date

Unknown

Last updated

2006-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Brief summary

the aim of this study is to measure brain metabolism in patients with lung cancer.FDG uptake in the brain in patients with malignant tumors will be compared to the amount of tracer activity found in patients who have benign pulmonary process. if differences between the brain uptake of FDG in the two groups will be found, further assessment will be performed in order to evaluate if such differences could be attributed and specifically localized to the brain regions innervated by the vagus

Interventions

DEVICEPET/CT imaging

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

35 Years to 70 Years

Healthy volunteers

Inclusion criteria

* patients with SPN referred for routine whole body FDG-PET imaging * patients with NSCLC and patients with no evidence of lung cancer on further follow up

Exclusion criteria

* patients with a clinical history of vagotomy, abdominal surgery. brain tumor, brain trauma or CVA. or those with a systemic inflammatory disease

Design outcomes

Primary

Measure	Time frame
the impact of the imaging modality on patients management	—

Secondary

Measure	Time frame
the impact of the imaging modality on patients management	—

Countries

Israel

Contacts

Primary ContactAlex Frenkel, Ph.D

a_frenkel@rambam.health.gov.il972-4-8543009

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026