Down Syndrome and Continuous Positive Pressure Therapy

Follow-up of the Therapeutic Coverage by Continuous Positive Pressure of the Obstructive Sleep Apnea Syndrome for Down Syndrome Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00394290

Acronym

Morphee

Enrollment

Registered

2006-11-01

Start date

2006-11-16

Completion date

2012-12-31

Last updated

2019-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Down Syndrome, Obstructive Sleep Apnea Syndrome

Keywords

Down Syndrome, Obstructive Sleep Apnea Syndrome, Continuous Positive Pressure, Hypersomnia

Brief summary

The purpose of this study is to evaluate the efficacy and tolerability of Continuous Positive Pressure for SAOS in Down Syndrome patients.

Interventions

DEVICEContinuous Positive Pressure

Nighttime continuous positive pressure device, to be used every day

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Down Syndrome patients with an Obstructive Sleep Apnea Syndrome * more than 18 years old

Exclusion criteria

* predictable non-compliance of device * non-compensated cardiopathy * non-stable thyroxin treatment * non-stable diabetes

Design outcomes

Primary

Measure	Time frame
Scores on psychometrical and dementia scales after a 3-month treatment period (and if possible, after 12 months)	0 and 3 months

Secondary

Measure	Time frame
Tolerability	0, 3 and 12 months

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026