Somatosensory Processing in Depression

Influence of Escitalopram on Somatosensory Processing in Patients With Major Depression

Status

Withdrawn

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00386893

Enrollment

Registered

2006-10-12

Start date

2006-10-31

Completion date

2011-12-31

Last updated

2015-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Brief summary

Aim of this study is to investigate neuronal differences (EEG/evoked potentials; functional MRI) between patients with major depression and healthy controls concerning brain activity after acute pain as well as changes of pain related brain activity during treatment with escitalopram.

Interventions

PROCEDUREsimultaneous EEG/fMRI

fMRI/EEG recordings

DEVICEfMRI

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Psychiatric in or outpatients with acute depressive episode * Indication for pharmacological treatment

Exclusion criteria

* Acute suicidal tendency * Neurological or severe somatic disorders * Women during pregnancy or lactation

Design outcomes

Primary

Measure	Time frame
changes in evoked potentials/functional MRI from baseline to week 4	two assessments, at baseline and week 4

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026