Breast Cancer
Conditions
Keywords
Breast Cancer Risk, Counseling, Prevention, Anxiety, BRCA1 mutation, BRCA2 mutation, Tamoxifen
Brief summary
To evaluate 1) the extent of patient overestimation of breast cancer development risk in subjects referred to a physician-based high-risk breast clinic; 2) the ability of physician counseling to improve patient risk perception and reduce psychological distress; 3) to identify factors relevant in clinical practice associated with increased distress and risk perception.
Detailed description
Patients referred to the Baystate Comprehensive Breast Center High-Risk Clinic wil, after giving consent, complete an intake evaluation of breast cancer risk, the patient's perceptions of breast cancer development risk, and the Brief Symptom Inventory-18. Physician history, physical and counseling then takes place, with sharing of risk estimates based on modified Gail model and Myriad tables regarding breast cancer risk and probability of BRCA1/2 mutation. After counseling, patients complete another assessment of risk perception and BSI-18, and again 2 months and 1 year post counseling. Recommendations for hormonal management and referral for formal genetic evaluation and testing will be tracked.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* Attendance at High-risk Clinic * Ability to complete BSI-18 and risk perception questionnaire
Exclusion criteria
* Diagnosis of invasive breast cancer * Diagnosis of ductal carcinoma in situ.
Countries
United States