A Comparison Study of Apadenoson and Adenosine to Treadmill Exercise Stress.

A Randomized, Double-Blind Comparison of Apadenoson and Adenosine to Treadmill Exercise Stress for Single-Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)

Status

Terminated

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00380198

Enrollment

1500

Registered

2006-09-25

Start date

2006-07-31

Completion date

2006-11-30

Last updated

2017-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Brief summary

The purpose of this clinical research study is to compare Apadenoson and adenosine to treadmill exercise stress SPECT MPI

Interventions

DRUGApadenoson

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

DIAGNOSTIC

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Clinically appropriate for exercise stress testing

Exclusion criteria

* Contraindication to adenosine stress or inability to perform treadmill exercise test

Design outcomes

Primary

Measure	Time frame
Agreement between MPI Summed Stress Scores for extent and severity of disease	—

Secondary

Measure	Time frame
Comparison of imaging data to 6 month event data or angiography	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026