A Comparison of Manual vs. Spontaneous Removal of the Placenta at Cesarean Section

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00375986

Enrollment

150

Registered

2006-09-13

Start date

2006-09-30

Completion date

2007-06-30

Last updated

2007-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section, Pregnancy

Keywords

Cesarean delivery, Placental removal, Blood loss

Brief summary

The purpose of this study is to determine if there are differences in operative blood loss with manual vs. spontaneous removal of the placenta during cesarean section.

Detailed description

Patients undergoing scheduled cesarean deliveries are randomized to manual or spontaneous placental removal.

Interventions

PROCEDUREManual placental removal at Cesarean delivery

PROCEDURESpontaneous placental removal at Cesarean delivery

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All term pregnant women 18 years of age and older undergoing scheduled cesarean delivery at Strong Memorial Hospital.

Exclusion criteria

* Prematurity (\<37 weeks) * Preoperative chorioamnionitis * Vaginal delivery of fetus * Emergency Cesarean Delivery * Patient's OB not agreeable to participating in this study.

Design outcomes

Primary

Measure	Time frame
Hematocrit levels (preoperatively and within 48 hours postoperatively)	—

Secondary

Measure	Time frame
Number of units of blood transfused intraoperatively and postoperatively	—
Development of uterine infection (endometritis)	—
Length of postoperative hospital stay	—
Operative time	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026