The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00374894

Enrollment

500

Registered

2006-09-12

Start date

2004-03-31

Completion date

2004-08-31

Last updated

2006-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lead Poisoning

Keywords

2,3-dimercaptosuccinic acid, Blood Lead Levels, children, multi-nutrients

Brief summary

Lead poisoning remains a common disease among children despite successful public health efforts that reduced its prevalence.Our study was designed to test the hypothesis that lead-poisoning children (BLLs:100-440µg/L) who were given DMSA and multi-nutrients would have a greater fall than children of other groups at 12 weeks of follow-up.

Interventions

DRUG2,3-dimercaptosuccinic acid

Study design

Observational model

DEFINED_POPULATION

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

3 Years to 6 Years

Inclusion criteria

* Initial BLLs 100-440µg/L * Age 3-6y * No more than two main residences * House cleaned (no lead contaminated) * Normal intake history and physical

Exclusion criteria

* Chelation in the past 12 weeks * Concomitant Fe deficiency(ferritin\<16ng/ml) * Hemoglobin\<10.5g/dL * Medications affecting mineral metabolism

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026