Type 1 Diabetes Mellitus
Conditions
Keywords
Cinnamon, Type 1 Diabetes, Adolescent, HbA1c
Brief summary
the purpose of this study is to determine if cinnamon improves glucose control among adolescents with type 1 diabetes mellitus.
Detailed description
Widespread achievement of glucose control remains an elusive goal for adolescents with Type 1 diabetes. Previous research has suggested that cinnamon may be effective at improving glucose control in type 2 diabetes. To date, no research has investigated the effect of cinnamon on type 1 diabetics. If the addition of a simple, natural, pill to a standard insulin regimen can significantly improve glucose control, the clinical implications would be substantial. Comparison: Using a prospective, double-blind, placebo-controlled design, 72 adolescent type I diabetics were treated with cinnamon (1 gram/day) or an equivalent appearing placebo for 90 days. HbA1c, total daily insulin intake, and adverse events were recorded and compared between groups.
Interventions
DRUGcinnamon
Sponsors
Dartmouth College
Dartmouth-Hitchcock Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE
Eligibility
Sex/Gender
ALL
Age
13 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
1. Diagnosis of Type 1 diabetes for \> 18 months prior to enrollment, 2. Age 13-18 years at the time of enrollment 3. Presenting to the clinic for routine care, 4. No hospital admissions for medical or psychiatric reasons in the 12 months prior to enrollment, 5. Accessible by phone, 6. Not pregnant.
Exclusion criteria
(1) Pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c | — |
Secondary
| Measure | Time frame |
|---|---|
| Total Daily Insulin | — |
| Carbohydrate/insulin dose | — |
| Hypoglycemic events | — |
| Compliance | — |
Countries
United States
Outcome results
None listed