Resistant Cystoid Macular Edema
Conditions
Keywords
Resistant uveitic cystoid macular edema, intravitreal triamcinolone, intravitreal bevacizumab
Brief summary
Cystoid macular edema (CME) is one of the common causes of vision loss in patients with UveitiS .Triamcinolone has been effectively used in reducing CME and improving the vision. Also there are some documents which recommend Bevacizumab(avastin) could reduce macular edema. This study compare intravitreous injection of triamcinolone and avastin in patients with resistant uveitic cystoid macular edema.
Detailed description
This study compare intravitreous injection of triamcinolone and avastin in patients with resistant uveitic cystoid macular edema.
Interventions
4 mg of Triamcinolone
DRUGIntravitreal injection of Avastin
Injection of 1.25 mg of Avastin and
Sponsors
Shahid Beheshti University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Uveitic CME * Uveitic CME refractory to routine treatment * Vision better than 5/200 and worse than 20/50
Exclusion criteria
* Mono- Ocular patients * History of vitrectomy * Glaucoma or ocular hypertension * History of other retinal disease that can cause macular edema * Pregnancy * Significant media opacity * Vision better than 20/50
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resorbed CME in OCT | every 3 month |
| Resorbed CME in clinical examination | Every 3 month |
Secondary
| Measure | Time frame |
|---|---|
| need to retreatment | when ever needed |
Countries
Iran
Outcome results
None listed