Effect of Percutaneous Botulinum Toxin A Injection on Natural Course of Upper Lid Retraction in Thyroid Eye Disease

Status

UNKNOWN

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00370734

Enrollment

Registered

2006-09-01

Start date

2005-05-31

Completion date

2007-02-28

Last updated

2007-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Keywords

botulinum toxin, thyroid eye disease, lid retraction

Brief summary

In active phase of thyroid eye disease some patients have obvious upper lid retraction , and sometimes exposure keratopathy .To date there is not any standard treatment for this situation . We are going to compare the natural course of the upper lid retraction with injection of botulinum toxin A injection to upper lid percutaneously.

Interventions

DRUGBotulinum toxin A injection

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* all the patients wiht oper lid retraction in active phase of thyroid ophthalmopathy

Exclusion criteria

* patients in non active phase

Countries

Iran

Contacts

Primary ContactBabak Babsharif, MD

labbafi@hotmail.com+98 21 22585952

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026