Diabetic Macular Edema
Conditions
Keywords
Bevacizumab, CSME, MPC, Triamcinolone acetonide
Brief summary
to compare the effect of intravitreal bevacizumab alone or in combination with triamcinolone acetonide with laser photocoagulation on clinically significant macular edema (CSME)
Detailed description
we entered 150 eyes into the study that recruitment of cases finished recently.Eligible eyes randomly assign to one of the study arms including intravitreal bevacizumzb, intravitreal bevacizumzb/triamcinolone and macular photocoagulation groups. Every patient needs at least 1 year followup. During this time BCVA, OCT, FA will be done for each patient and inaccording to interpretation of datas and fundus exam repeatation of injection will be done.
Interventions
DRUGbevacizumab
DRUGtriamcinolone acetonide
Sponsors
Shahid Beheshti University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* case with clear media IOP below 23 mm/Hg female after menopause at least for 12 months or had 2 contraceptive roots visual acuity between 20/50 to 20/320
Exclusion criteria
* no PRP or N.d YAG laser in past 6 months no intraocular surgery in past 12 months * CVA in past 12 months blood sugar above 250 * active infection in extraocular adnexa
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual acuity | — |
| central macular thickness | — |
Secondary
| Measure | Time frame |
|---|---|
| Leakage in fluorescein angiography | — |
| intraocular pressure | — |
| cataract progression | — |
| anterior chamber reaction | — |
Countries
Iran
Contacts
Primary ContactMasoud Soheilian, MD
Outcome results
None listed