Branch Retinal Vein Occlusion
Conditions
Keywords
Macular edema, Branch retinal vein occlusion, Intravitreal triamcinolone, Macular thickness, Retinal neovascularization
Brief summary
The purpose of this study is to determine whether intraocular injection of triamcinolone is effective in the treatment of macular edema in acute branch retinal vein occlusion.
Detailed description
Intravitreal triamcinolone has recently been shown to have beneficial effect on chronic macular edema due to vein occlusion and preventive effect on neovascularization. Hypothetically, prevention of macular derangement by reducing the amount of edema from early phase after occlusion until restoration of collaterals seems to be helpful in these eyes. To our knowledge, no prospective randomized clinical trial, considering both macular changes and preventive effect on neovascularization has been published for intravitreal triamcinolone in acute branch retinal vein occlusion.
Interventions
DRUGTriamcinolone
Sponsors
Shahid Beheshti University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Eyes suffering from branch retinal vein occlusion with less than 2 months duration.
Exclusion criteria
* Monocularity, * Previous intraocular surgery or laser therapy * Glaucoma or ocular hypertension * Significant media opacity * Existence of traction on the macula * Visual acuity ≥20/40 * Signs of chronicity (such as cilioretinal and/or retinal shunt vessels)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Central macular thickness | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual acuity | — |
| Retinal neovascularization | — |
| Intraocular pressure | — |
| Cataract progression | — |
Countries
Iran
Outcome results
None listed