Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment

Status

UNKNOWN

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00370201

Enrollment

Unknown

Registered

2006-08-31

Start date

2004-03-31

Completion date

2006-08-31

Last updated

2006-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhegmatogenous Retinal Detachment

Keywords

retinal detachment, proliferative vitreoretinopathy

Brief summary

This clinical trial will test the efficacy and safety of oral colchicine in prevention of proliferative vitreoretinopathy (PVR) in cases of rhegmatogenous retinal detachment

Interventions

DRUGcolchicine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Rhegmatogenous retinal detachment

Exclusion criteria

* PVR grade C * Duration of retinal detachment ≥ one month * History of cataract surgery * History of RD surgery

Design outcomes

Primary

Measure	Time frame
proliferative vitreoretinopathy	—
retinal reattachment rate	—

Secondary

Measure	Time frame
visual acuity	—
reoperation	—
macular pucker	—

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026