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Cost Effective Treatment for Dually Diagnosed Homeless

Cost Effective Treatment for Dually Diagnosed Homeless

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00368524
Enrollment
160
Registered
2006-08-24
Start date
2001-11-30
Completion date
2005-11-30
Last updated
2023-03-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine Dependence, Homelessness, Mental Disorder, Unemployment

Keywords

cocaine dependence, mental disorder, dual diagnoses, homelessness

Brief summary

This randomized controlled trial examined whether an abbreviated treatment using abstinence contingency management for housing and work/training (CM, n=103) with cocaine dependent, non-psychotic, dually diagnosed homeless persons, would show non-inferior outcomes compared to the full treatment (CM+, n=103). It was hypothesized that CM+ would show superior abstinence and retention outcomes, but that CM, with components derived from previously effective behavioral day treatment, would obtain non-inferior outcomes, defined as 75% or more of those observed for the full treatment (CM+) during active treatment months 1-6. The CM+ included all CM components but added behavioral day treatment that included voucher reinforcement of $7.50-15.00, for objective weekly therapeutic goal attainment in five domains of functioning: drug dependence, homelessness, unemployment, non-drug related recreational activities, and behavioral, health, or mental health problems. Abstinence was assessed by observed urine specimen collection and weekly testing weeks 1-52, and randomly, bi-monthly for months 13-18. Abstinence, homelessness, employment and other outcomes were also assessed at baseline, 2, 6, 12, and 18 months.

Interventions

BEHAVIORALcontingency management and behavioral day treatment

Sponsors

University of Alabama at Birmingham
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

McKinney Act criteria for homelessness; DSM IV diagnosis for Cocaine Dependence; self-reported use within the last 2 weeks; psychological distress indicated by score of 70 on 1 or more Brief Symptom Inventory scales; willingness to participate; no plans to move from Birmingham area for 18 months; \-

Exclusion criteria

cognitive impariment precluding informed consent; requiring immediate inpatient medical treatment

Design outcomes

Primary

MeasureTime frame
abused drug abstinence measured by observed urine specimen testing weeks 1-52, and bimonthly months 13-18

Secondary

MeasureTime frame
abstinence, housing, employment and other outcomes at 0, 2, 6, 12 and 18 months.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 7, 2026