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Nasogastric Tube vs. Orogastric Feeding Tube in Preterm Infants: Which is Best?

Nasogastric Tube vs. Orogastric Feeding Tube in Preterm Infants: Which is Best?

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00365703
Enrollment
115
Registered
2006-08-17
Start date
2006-09-30
Completion date
2007-08-31
Last updated
2007-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant, Premature

Keywords

Infant, Premature, Tube feeding

Brief summary

The purpose of this study is to find out which method (nasogastric vs. orogastric) of feeding tube for premature infants results in earlier only oral feeding.

Detailed description

Preterm infants, even as young as 23 weeks gestational age, can be fed enterally at the first week of life. Coordination of sucking and swallowing, and coordination of both and breathing is necessary for efficient and safe oral feeding, and is not well established before the 35th week gestational age. That is why tube feeding is essential for preterm infants younger than that age. There is no consensus regarding the best way for the feeding tube, i.e. oral vs. nasal, and whether placing the tube should be continuous or intermittently. Nasogastric tube has been associated with vagal responses. Both tubes may cause gastric perforation. Development and function of oral feeding has been described. It is known that non-nutritive sucking and early introduction of oral feeding accelerate the transition from tube feeding to oral feeding. It is suggested that the preterm infant may experience a maturational lag in vagal function related to ingestive needs, which may contribute to continued feeding difficulties and may be a measurable marker of subtle neurodevelopmental problems. Both oral and nasal feeding tube may interfere with establishment of efficient oral feeding. The purpose of this study is to see whether there is a difference between oral and nasal tube feeding, regarding the institution of oral feeding.

Interventions

1. Orogastric feeding tube 2. Nasogastric feeding tube

Sponsors

Hillel Yaffe Medical Center
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
No minimum to 4 Months
Healthy volunteers
No

Inclusion criteria

* All preterm infants, born during one year, who required tube feeding, and later discharged from neonatal intensive care unit.

Exclusion criteria

* Infants who died during hospitalization * Infants with severe neurologic deficit (e.g. after Sarnat II-III asphyxia, or as a part of a syndrome * Infants with gastrostomy * Infants who were transferred to another hospital for any reason (e.g. heart surgery)

Design outcomes

Primary

MeasureTime frame
The mean post conceptual age at which the infant is fed orally only.1 year

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026