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Progression of Hematopoietic Diseases in Shanghai, China

Analysis of Disease Progression for Aplastic Anemia, Myelodysplastic Syndrome, Acute Myeloid Leukemia and Benzene Poisoning in Shanghai, China.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00365014
Enrollment
10757
Registered
2006-08-16
Start date
2003-08-31
Completion date
2009-12-31
Last updated
2013-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematologic Diseases

Keywords

aplastic anemia, myelodysplastic syndromes, cytopenias, acute myeloid leukemia, myelodysplastic/myeloproliferative diseases, benzene poisoning

Brief summary

The purpose of this study is to identify and characterize blood diseases presenting at Shanghai hospitals and to compare them with respect to clinical presentation, phenotype, molecular characteristics, benzene or other exposures and genetic susceptibility.

Detailed description

The purpose of this study is to identify and characterize blood diseases presenting at Shanghai hospitals and to compare them with respect to clinical presentation, phenotype, molecular characteristics, benzene or other exposures and genetic susceptibility. The format for these studies is a set of clinical series superimposed on a case-control design that enables integration of detailed clinical and molecular characterizations of disease pathogenesis together with an evaluation of potential confounding and interacting factors within a structured statistical analysis of benzene exposure.

Interventions

None listed

Sponsors

Fudan University
CollaboratorOTHER
University of Cincinnati
CollaboratorOTHER
ExxonMobil Biomedical Sciences, Inc.
CollaboratorINDUSTRY
British Petroleum P.L.C.
CollaboratorINDUSTRY
Chevron Corporation
CollaboratorINDUSTRY
ConocoPhillips
CollaboratorINDUSTRY
Exxon Mobil
CollaboratorINDUSTRY
Marathon Ashland
CollaboratorUNKNOWN
Shell Chemicals
CollaboratorINDUSTRY
University of Colorado, Denver
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Men and women 18 years or older Diagnosis of hematologic abnormality

Exclusion criteria

Children Non hematologic diseases

Design outcomes

Primary

MeasureTime frameDescription
blood diseases presenting at Shanghai hospitalshospital staycharacterization of people with blood diseases presenting at Shanghai hospitals

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026