Skip to content

Cardiovascular Disease Risk Factors in Chinese American Immigrants

Chinese American Cardiovascular Health Assessment CHA-CHA

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00362128
Acronym
CHA-CHA
Enrollment
2072
Registered
2006-08-09
Start date
2007-01-31
Completion date
2009-10-31
Last updated
2020-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases, Diabetes Mellitus, Hypertension, Metabolic Syndrome X

Keywords

Blood Pressure, High, Obesity, Tobacco Use Disorder

Brief summary

The Chinese population is currently the fastest growing ethnic group in New York City (NYC). Research has shown that Chinese immigrants living in NYC have higher rates of cardiovascular disease (CVD) than individuals in China. This study will evaluate the effect that acculturation has on health habits and CVD risk factors in Chinese immigrants living in NYC.

Detailed description

CVD includes diseases that affect the heart and blood vessels. The underlying cause of CVD is atherosclerosis, in which fatty plaques develop on the inner walls of arteries. There are many risk factors for CVD, including inflammation, high blood pressure, high cholesterol, and obesity. Research has shown that CVD mortality rates differ greatly between Chinese immigrants living in NYC and individuals living in China. Because of this difference, it is important to understand the impact of immigration and acculturation on health habits and psychosocial factors, which may influence the development of CVD. This study will gather information from Chinese immigrants in NYC to identify the impact of immigration and acculturation on behavior and CVD risk factors. In addition, results from this study may provide insight into the CVD risk patterns in other immigrant groups. This study will enroll Chinese immigrants living in NYC. Participants will attend one study visit and will complete questionnaires to assess their health habits (diet, physical activity, and smoking), stress levels, and socioeconomic status. Participants will also undergo a physical examination and blood collection.

Interventions

None listed

Sponsors

National Heart, Lung, and Blood Institute (NHLBI)
CollaboratorNIH
Albert Einstein College of Medicine
Lead SponsorOTHER

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Chinese immigrant * Currently residing in NYC

Exclusion criteria

* Under 18 years of age * Not of Chinese dissent * Born outside mainland China

Design outcomes

Primary

MeasureTime frameDescription
Number of Participants With Hypertension4 yearsSystolic BP above 129 or Diastolic BP above 79.

Countries

United States

Participant flow

Participants by arm

ArmCount
Observational
The study design was a cross-sectional observational cohort design.
2,072
Total2,072

Baseline characteristics

CharacteristicObservational
Age, Categorical
<=18 years
0 Participants
Age, Categorical
>=65 years
390 Participants
Age, Categorical
Between 18 and 65 years
1682 Participants
Age, Continuous53 years
Region of Enrollment
United States
2072 participants
Sex: Female, Male
Female
1093 Participants
Sex: Female, Male
Male
979 Participants

Adverse events

Event typeEG000
affected / at risk
deaths
Total, all-cause mortality
— / —
other
Total, other adverse events
0 / 2,072
serious
Total, serious adverse events
0 / 2,072

Outcome results

Primary

Number of Participants With Hypertension

Systolic BP above 129 or Diastolic BP above 79.

Time frame: 4 years

ArmMeasureValue (NUMBER)
ObservationalNumber of Participants With Hypertension532 participants

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026