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Effects of Nerve Block on Knee Function After Knee Replacement

Effects of Continuous Lumbar Plexus Nerve Block on Functional Restoration and Outcome After Unilateral Total Knee Arthroplasty

Status
Withdrawn
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00358241
Enrollment
0
Registered
2006-07-31
Start date
Unknown
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

Nerve block, postoperative pain, analgesia

Brief summary

Early physical therapy after knee surgery is very painful on top of pain from surgery. Pain following surgery can limit recovery. One way to treat pain is by giving intravenous (IV) pain medication with morphine. Another method is to use a nerve block which involves placing a thin catheter (tube) into the lower back near the nerves that sense pain in the knee and give a local anesthetic to numb the nerves. Sometimes both methods are used together. This research is being done to determine whether nerve blocks with a local anesthetic improve knee recovery in addition to providing pain relief as compared to IV pain medicine alone

Interventions

PROCEDURENerve block

Sponsors

Johns Hopkins University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
DOUBLE

Eligibility

Sex/Gender
ALL
Age
21 Years to 80 Years

Inclusion criteria

* Age 21-80 year old * ASA Physical Status ASA I and II * Mentally competent * Intellectually competent * Body mass index \<35 * No severe cardiac diseases * No severe pulmonary diseases * Unilateral knee disease * No other lower extremity joint disease * No chronic narcotic therapy or illicit drug use

Exclusion criteria

* Age \<21 or \>80 year old * ASA Physical Status \>ASA II * Mentally incompetent * Intellectually incompetent or cognitively impaired * Non-English speaking patient * Worker's compensation patient * Body mass index \> 35 * Bilateral knee disease * Has other lower extremity joint disease * Severe cardiac diseases * Severe pulmonary diseases * Chronic narcotic therapy or illicit drug use * Pregnancy

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026