Decompensated Heart Failure
Conditions
Brief summary
HF is associated with repeated hospitalisations and poor prognosis.The aim of this study is to investigate whether BNP-guided care (BGC) in addition to multidisciplinary management(MM) improves outcome compared to HNC alone or usual care (UC) for decompensated HF patients after discharge. Patients hospitalised with cardiac decompensation in 9 Viennese hospitals are randomised to BGC, MM alone, or UC. MM includes 2 consultations of a heart failure (HF) specialist 10 days and 2 months after discharge for recommending medical optimisation and care by a specialised HF nurse including 4 home visits and telephone contact. In addition, BGC includes intensified increase of medical treatment during repeated follow-up visits in a HF clinic in patients with an Nt-BNP level above 2200pg/ml at discharge.
Interventions
PROCEDUREBNP-guided care in addition to multidisciplinary management
Sponsors
Medical University of Vienna
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Clinical signs and symptoms of cardiac decompensation during the present hospitalisation 2. NYHA class III or IV at time of admission 3. Cardiothoracic ratio \> 0.5, and/or left ventricular ejection fraction \<40% documented by echocardiography
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart failure rehospitalisation rate; | — |
| combined endpoint death or heart failure rehospitalisation; | — |
Outcome results
None listed