Effect of Two Iron Preparations on Protein in the Urine

A Randomized Cross-over Pilot Study of the Effect of Sodium Ferric Gluconate Complex vs. Iron Sucrose on Proteinuria in Non-dialysis Chronic Kidney Disease Patients

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00354692

Enrollment

Registered

2006-07-20

Start date

2006-06-30

Completion date

Unknown

Last updated

2012-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia, Iron-Deficiency, Kidney Failure, Chronic

Brief summary

This pilot study will compare the effects of sodium ferric gluconate complex and iron sucrose on urine concentrations of various chemicals including protein

Interventions

DRUGSodium Ferric Gluconate and Iron sucrose

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Moderate to severe anemia * Iron deficiency * Moderate to severe chronic kidney disease * Age ≥ 18 or greater and able to give informed consent

Exclusion criteria

* Receiving dialysis * Known sensitivity to Sodium Ferric Gluconate Complex in Sucrose Injection, Iron sucrose USP, or any of their components * Clinically unstable * Indication of iron sufficiency

Design outcomes

Primary

Measure	Time frame
Change in urine protein	180 minutes

Secondary

Measure	Time frame
Change in various urine chemicals	180 minutes

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026