Detection of Pulmonary Embolism With CECT

Detection of Pulmonary Embolism Comparing Isovue-370 and Visipaque 320 Using 64-Slice Multi-Detector Computed Tomographic Angiography

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00351754

Enrollment

120

Registered

2006-07-13

Start date

2006-07-31

Completion date

2006-11-30

Last updated

2008-01-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Embolism

Brief summary

To compare the vascular enhancement of the two contrast agents in pulmonary Multi-detector CTA

Interventions

DRUGIsovue

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients 18 yrs or older * With suspected PE * Referred for MDCTA of pulmonary arteries * Signed informed consent

Exclusion criteria

* Pregnant and lactating females * History of hypersensitivity to iodinated contrast agents * Hyperthyroidism or pheochromocytoma * Severe CHF * Renal impairment * Weight greater than 300 lbs * Pacemaker * Swan Ganz catheter * Defibrillator or other intrathoracic metallic vascular device * Received an investigational compound within 30 days of being in the study

Design outcomes

Primary

Measure	Time frame
Hounsfield Units (HU) measured at various levels of pulmonary arteries	—

Secondary

Measure	Time frame
Presence of artifacts; global enhancement	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026