BBC ONE - British Bifurcation Coronary Study

British Bifurcation Coronary Study - Old, New and Evolving Strategies.

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00351260

Acronym

BBC ONE

Enrollment

500

Registered

2006-07-12

Start date

2005-01-31

Completion date

2007-12-31

Last updated

2008-04-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina, Ischaemic Heart Diseases, Stenosis

Keywords

Bifurcation, Coronary, Stenosis, Stent, drug elution

Brief summary

The study aims to assess whether a SIMPLE or a COMPLEX strategy is best for the treatment of coronary bifurcation stenoses.

Detailed description

500 patients will be randomised to either a SIMPLE strategy (provisional T stenting) or a COMPLEX strategy (crush or culotte stenting) with clinical follow-up at 9 months.

Interventions

PROCEDURECoronary Angioplasty

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

\>18 years * Coronary Bifurcation Lesion requiring treatment

Exclusion criteria

* Cardiogenic Shock * Acute MI * Additional type C lesion for Rx platelets \<50 * LVEF \<20%

Design outcomes

Primary

Measure	Time frame
Death	—
Myocardial infarction	—
Target vessel revascularisation	—

Secondary

Measure	Time frame
Repeat angiography	—
Stent thrombosis	—

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026