Ophthalmic Surgery
Conditions
Brief summary
Comparison of 1 day versus 1 hour application of topical Zymar.
Interventions
DRUGZymar
zymar qid
Sponsors
Stanford University
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ophthalmic surgery
Exclusion criteria
* taken antibiotics, allergic to fluoroquinolones
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of Participant With Positive Culture | 2 weeks |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| 1 Day of Gatifloxacin eyes receiving gatifloxacin 4 times per day 1 day before surgery | 60 |
| Total | 60 |
Baseline characteristics
| Characteristic | 1 Day of Gatifloxacin |
|---|---|
| Age, Continuous | 68 years |
| Sex: Female, Male Female | 25 Participants |
| Sex: Female, Male Male | 35 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 0 / 60 |
| serious Total, serious adverse events | 0 / 60 |
Outcome results
Primary
Number of Participant With Positive Culture
Time frame: 2 weeks
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| 1 Day of Gatifloxacin | Number of Participant With Positive Culture | 17 participants |