Osteoarthritis, Rheumatoid Arthritis
Conditions
Keywords
inflammatory arthritis, rheumatoid arthritis, knee osteoarthritis, arthritis, yoga
Brief summary
The purpose of this study is to evaluate the impact of yoga on inflammatory arthritis and knee osteoarthritis.
Detailed description
Yoga is a set of ancient Indian theories and practices, focusing on unifying mind, body, and spirit, and promoting strength, balance, and flexibility. The physical aspect of yoga includes poses, breathing techniques, and relaxation. Inflammatory arthritis, a chronic disease characterized by inflammation of the lining of the joints, can cause long-term joint damage, resulting in chronic pain, loss of function, and disability. The primary objective of this study is to learn how people with inflammatory arthritis and knee osteoarthritis respond to an exercise program of yoga. To accomplish this, 30 persons with inflammatory arthritis or knee osteoarthritis will be randomly assigned to one of two groups. Group one will begin an immediate 8-week program of yoga classes consisting of 60-minute sessions, twice a week. Group two, or the waitlist control group, will receive 8 weeks of arthritis education followed by the same 8-week yoga program as group one. Participants also will have blood drawn, and complete various tests. The yoga classes will be taught by an experienced, certified yoga instructor, and are designed especially for the needs of people with inflammatory arthritis and knee osteoarthritis. This study will provide important data on integrating mind-body activities into the treatment of inflammatory arthritis and knee osteoarthritis.
Interventions
BEHAVIORALyoga
8-week yoga program.
Sponsors
National Center for Complementary and Integrative Health (NCCIH)
Johns Hopkins University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
Assessors masked to study condition
Intervention model description
Randomized controlled trial
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 18+ (RA only upper age limit 70) * Confirmed or probable OA (using pre-specified criteria) OR Rheumatoid arthritis (participation approved by rheumatologist) * Currently sedentary (physically active for 20 min \< 3times/week)
Exclusion criteria
* Inability to ambulate without use of assistive device * Uncontrolled high blood pressure or existing heart condition * Co-morbid inflammatory condition with overlapping symptoms (i.e., fibromyalgia) * Surgery within 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Physical Health | baseline, post intervention, follow-up | Assessed using SF36 Physical Component Score |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mobility/Fitness | baseline, posttest, follow-up | Change in flexibility, balance, strength, walk time |
| RA Disease Activity | baseline, post intervention, follow-up | DAS28 CRP score |
| Psychological Function | baseline, , posttest, follow-up | Change in SF36 MCS, CES-D, PANAS, Perceived Stress and Arthritis Self Efficacy |
| HRQL | baseline, post intervention, follow-up | Change in SF36 domains |
Countries
United States
Outcome results
None listed