Prophylactic Laser Treatment of Drusen Maculopathy

Prophylactic Laser Treatment of Drusen Maculopathy in Age-related Macular Degeneration.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00348543

Enrollment

150

Registered

2006-07-04

Start date

1999-12-31

Completion date

2006-10-31

Last updated

2011-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Age-related Macular Degeneration

Keywords

age-related macula degeneration, prophylactic laser treatment, exudative complication

Brief summary

To study the effect of mild laser treatment on the incidence of exudative complications in soft drusen maculopathy. We hypothesise that mild laser treatment causing a proliferation of the retinal pigment epithelium and enhancing the capacity of clearing drusen material from Bruch's membrane.

Interventions

PROCEDURElaser treatment

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

55 Years to No maximum

Healthy volunteers

Inclusion criteria

* \> 55 years of age, * Soft drusen maculopathy, * VA 0.8-1.0

Exclusion criteria

* VA \<0.8, * Pigment clumps, * PED, * CNV, * Atrophy, * Haemorrhage, * Diabetes retinopathy, * Sign cataract, * Glaucoma

Design outcomes

Primary

Measure	Time frame
Change in visual acuity	—

Secondary

Measure	Time frame
incidence of exudative complications	—

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026