Safety/Efficacy of Systane Free vs Refresh Liquigel

An Evaluation of the Safety and Efficacy of Systane Free FID 105783

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00348517

Enrollment

100

Registered

2006-07-04

Start date

2006-07-31

Completion date

2006-11-30

Last updated

2012-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye

Brief summary

The objective of this study is to evaluate the safety and efficacy of Systane Free FID 105783 when compared to Refresh Liquigel Lubricant Eye Drops (Allergan) in a specified population of dry eye patients.

Interventions

OTHERSystane Free Lubricant Eye Drops

1-2 drops per eye four times per day for 42 days

OTHERRefresh Liquigel Lubricant Eye Drops

1-2 drops per eye four times per day for 42 days

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* \>/= 3 corneal staining score using NEI scoring system. * Need artificial tears at least some of the time. * Other protocol-defined inclusion criteria may apply.

Exclusion criteria

* History or evidence of ocular or intraocular surgery in either eye within the past six months. * History of intolerance or hypersensitivity to any component of the study medication. * Use of Restasis within 30 days of Visit 1. * Participation in an investigational drug or device study within 30 days of entering this study. * Other protocol-defined

Design outcomes

Primary

Measure	Time frame
Change in corneal staining at Day 28 from baseline (Day 0)	Day 28

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026