Product Preference With Systane Compared to Artificial Tears on Frequency of Drop Use

The Effect of Systane® Compared to Marketed Artificial Tears on Frequency of Drop Use

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00347984

Enrollment

Registered

2006-07-04

Start date

2005-12-31

Completion date

2006-02-28

Last updated

2012-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye

Brief summary

The objective of this study was to evaluate the effect of Systane® compared to marketed artificial tears on the frequency of drop use.

Interventions

OTHERSystane Lubricant eye drops

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Subjects age 18 (minimum); reported history of dry eye syndrome in both eyes; TFBUT ≤ 7 seconds in at least 1 eye at Visit 1; ≥ 1+ fluorescein staining score in any region in at least 1 eye at Visit 1; desire to use an artificial tear substitute for dry eye symptoms at least 4 times per day at Visit 1 and Visit 2.

Exclusion criteria

* Age less than 18 years

Design outcomes

Primary

Measure	Time frame
Frequency of drop use and/or desire to use; Drop preference	—

Secondary

Measure	Time frame
Product questionnaire; Symptoms; Corneal and conjunctival staining; Tear film break-up time (TFBUT).	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026