Tramadol iv. : Influence of Dose and Dose Intervals on Therapeutic Accuracy and Side Effects When Used for Postoperative Pain Relief in Ambulatory Surgery

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00333346

Enrollment

200

Registered

2006-06-05

Start date

2006-09-30

Completion date

2009-04-30

Last updated

2010-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ambulatory Surgery

Brief summary

The aim of this study is to compare the administration of 1 unit dose of 100 mg tramadol intravenously versus multiple smaller dosages of tramadol during the first 6 hours post-operatively and to investigate the time course and accuracy of pain relief versus the onset and duration of side-effects.

Interventions

DRUGAdministration of tramadol intravenously

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* ASA I and II female or male patients * Aged 18-70 years * Scheduled for ambulatory surgery requiring postoperative pain medication.

Exclusion criteria

* Weight less than 70% or more than 130% of ideal body weight * Neurological disorder * Recent use of psycho-active medication, including alcohol * Patients suffering from chronic pain receiving pre-operative pain medication including NSAID's * Use of chronic anti-emetic medication, use of chronic corticoid therapy

Design outcomes

Primary

Measure	Time frame
Time course of pain relief	—
Accuracy of pain relief	—
Onset of side-effects	—
Duration of side-effects	—

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026