A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00333125

Enrollment

319

Registered

2006-06-02

Start date

2006-04-30

Completion date

2007-02-28

Last updated

2016-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma, Ocular Hypertension

Brief summary

The purpose of this study is to compare the intraocular pressure (IOP)-lowering efficacy and safety of two combination products in patients with open-angle glaucoma or ocular hypertension.

Interventions

DRUGTravoprost 40 mcg/ml + Timolol 5 mg/ml eye drops, solution (DuoTrav)

One drop in the study eye(s) once daily, 9 PM, for 6 weeks

DRUGDorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (Cosopt)

One drop in the study eye(s) twice daily for 6 weeks

OTHERTimolol Vehicle

One drop in the study eye(s) once daily for 6 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* 18 or older. * Diagnosis of glaucoma or ocular hypertension. * Other protocol-defined inclusion criteria may apply.

Exclusion criteria

* Under 18. * Other protocol-defined

Design outcomes

Primary

Measure	Time frame
Mean Intra-Ocular Pressure (IOP)	6 weeks

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026